Common systemic features preceding the rash included fever (62%), lethargy (41%), myalgia (31%), and headache (27%) lymphadenopathy was also common (reported in 56%). In this case series, 95% of the persons presented with a rash (with 64% having ≤10 lesions), 73% had anogenital lesions, and 41% had mucosal lesions (with 54 having a single genital lesion).
Transmission was suspected to have occurred through sexual activity in 95% of the persons with infection. Overall, 98% of the persons with infection were gay or bisexual men, 75% were White, and 41% had human immunodeficiency virus infection the median age was 38 years. We report 528 infections diagnosed between April 27 and June 24, 2022, at 43 sites in 16 countries. We formed an international collaborative group of clinicians who contributed to an international case series to describe the presentation, clinical course, and outcomes of polymerase-chain-reaction–confirmed monkeypox virus infections. Transmission, risk factors, clinical presentation, and outcomes of infection are poorly defined. Currently, cases are occurring worldwide. Original Article Monkeypox Virus Infection in Humans across 16 Countries - April–June 2022 List of authors.īefore April 2022, monkeypox virus infection in humans was seldom reported outside African regions where it is endemic. The most trusted, influential source of new medical knowledge and clinical best practices in the world.
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